View source for 1nec


==NITROREDUCTASE FROM ENTEROBACTER CLOACAE==
<StructureSection load='1nec' size='340' side='right' caption='[[1nec]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1nec]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NEC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nec OCA], [http://pdbe.org/1nec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nec RCSB], [http://www.ebi.ac.uk/pdbsum/1nec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nec ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NFNB_ENTCL NFNB_ENTCL]] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/1nec_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nec ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bryant, C]]
[[Category: Erdmann, H]]
[[Category: Hecht, H J]]
[[Category: Pelletier, H]]
[[Category: Sawaya, R]]
[[Category: Flavoprotein]]
[[Category: Fmn]]
[[Category: Oxidoreductase]]