View source for 3c29


==Cre-loxP Synaptic structure==
<StructureSection load='3c29' size='340' side='right' caption='[[3c29]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3c29]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_p1 Bacteriophage p1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C29 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hof|2hof]], [[3c28|3c28]], [[4crx|4crx]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cre ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10678 Bacteriophage P1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c29 OCA], [http://pdbe.org/3c29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c29 RCSB], [http://www.ebi.ac.uk/pdbsum/3c29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c29 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1]] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c2/3c29_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c29 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacteriophage p1]]
[[Category: Duyne, G D.Van]]
[[Category: Ghosh, K]]
[[Category: Di-aminopurine]]
[[Category: Dna integration]]
[[Category: Dna recombination]]
[[Category: Recombination-dna complex]]
[[Category: Synapsis]]