View source for 2eyf


==Crystal structure of Staphylococcal nuclease mutant T44V==
<StructureSection load='2eyf' size='340' side='right' caption='[[2eyf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2eyf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EYF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EYF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[2exz|2exz]], [[2ey1|2ey1]], [[2ey2|2ey2]], [[2ey5|2ey5]], [[2ey6|2ey6]], [[2eyh|2eyh]], [[2eyj|2eyj]], [[2eyl|2eyl]], [[2eym|2eym]], [[2eyo|2eyo]], [[2eyp|2eyp]], [[2f0d|2f0d]], [[2f0e|2f0e]], [[2f0f|2f0f]], [[2f0g|2f0g]], [[2f0h|2f0h]], [[2f0i|2f0i]], [[2f0j|2f0j]], [[2f0k|2f0k]], [[2f0l|2f0l]], [[2f0m|2f0m]], [[2f0n|2f0n]], [[2f0o|2f0o]], [[2f0p|2f0p]], [[2f0q|2f0q]], [[2f0s|2f0s]], [[2f0t|2f0t]], [[2f0u|2f0u]], [[2f0v|2f0v]], [[2f0w|2f0w]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nuc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eyf OCA], [http://pdbe.org/2eyf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eyf RCSB], [http://www.ebi.ac.uk/pdbsum/2eyf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eyf ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ey/2eyf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eyf ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Micrococcal nuclease]]
[[Category: Lu, J Z]]
[[Category: Sakon, J]]
[[Category: Stites, W E]]
[[Category: Calcium]]
[[Category: Dna hydrolase]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Rna hydrolase]]
[[Category: Signal]]