View source for 1ype

[[Image:1ype.gif|left|200px]]

 {{Structure
|PDB= 1ype |SIZE=350|CAPTION= <scene name='initialview01'>1ype</scene>, resolution 1.81&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>, <scene name='pdbligand=UIP:(1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL-1-ETHYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE'>UIP</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span>
|GENE= 
|DOMAIN=
|RELATEDENTRY=[[1y3w|1Y3W]], [[1yp9|1YP9]], [[1ypg|1YPG]], [[1ypj|1YPJ]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ype FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ype OCA], [http://www.ebi.ac.uk/pdbsum/1ype PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ype RCSB]</span>
}}

'''Thrombin Inhibitor Complex'''


==About this Structure==
1YPE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPE OCA]. 

==Reference==
A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates., Fokkens J, Klebe G, Angew Chem Int Ed Engl. 2006 Jan 30;45(6):985-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16374786 16374786]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Thrombin]]
[[Category: Diederich, F.]]
[[Category: Fokkens, J.]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Obst-Sander, U.]]
[[Category: 6 stranded beta-sheet]]
[[Category: barrel]]
[[Category: inhibitor complex]]
[[Category: thrombin]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:16:39 2008''