View source for 1xio

[[Image:1xio.jpg|left|200px]]

 {{Structure
|PDB= 1xio |SIZE=350|CAPTION= <scene name='initialview01'>1xio</scene>, resolution 2.000&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=PEE:PHOSPHATIDYLETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>
|ACTIVITY= 
|GENE= 
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xio OCA], [http://www.ebi.ac.uk/pdbsum/1xio PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xio RCSB]</span>
}}

'''Anabaena sensory rhodopsin'''


==Overview==
Microbial sensory rhodopsins are a family of membrane-embedded photoreceptors in prokaryotic and eukaryotic organisms. Structures of archaeal rhodopsins, which function as light-driven ion pumps or photosensors, have been reported. We present the structure of a eubacterial rhodopsin, which differs from those of previously characterized archaeal rhodopsins in its chromophore and cytoplasmic-side portions. Anabaena sensory rhodopsin exhibits light-induced interconversion between stable 13-cis and all-trans states of the retinylidene protein. The ratio of its cis and trans chromophore forms depends on the wavelength of illumination, thus providing a mechanism for a single protein to signal the color of light, for example, to regulate color-sensitive processes such as chromatic adaptation in photosynthesis. Its cytoplasmic half channel, highly hydrophobic in the archaeal rhodopsins, contains numerous hydrophilic residues networked by water molecules, providing a connection from the photoactive site to the cytoplasmic surface believed to interact with the receptor's soluble 14-kilodalton transducer.

==About this Structure==
1XIO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XIO OCA]. 

==Reference==
Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A., Vogeley L, Sineshchekov OA, Trivedi VD, Sasaki J, Spudich JL, Luecke H, Science. 2004 Nov 19;306(5700):1390-3. Epub 2004 Sep 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15459346 15459346]
[[Category: Anabaena sp.]]
[[Category: Single protein]]
[[Category: Luecke, H.]]
[[Category: Vogeley, L.]]
[[Category: photoreceptor]]
[[Category: signaling protein]]

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