View source for 5cc4


==Crystal structure of Staphylococcal nuclease variant Delta+PHS T62E/V66E at cryogenic temperature==
<StructureSection load='5cc4' size='340' side='right' caption='[[5cc4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5cc4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CC4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=THP:THYMIDINE-3,5-DIPHOSPHATE'>THP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bdc|3bdc]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cc4 OCA], [http://pdbe.org/5cc4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cc4 RCSB], [http://www.ebi.ac.uk/pdbsum/5cc4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cc4 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. 
__TOC__
</StructureSection>
[[Category: Micrococcal nuclease]]
[[Category: Bell-Upp, P C]]
[[Category: E., B Garcia-Moreno]]
[[Category: Schlessman, J L]]
[[Category: Skerritt, L A]]
[[Category: Hydrolase]]
[[Category: Hyperstable]]
[[Category: Ionizable group]]
[[Category: Nuclease]]
[[Category: Pdtp]]