View source for 5pvh


==PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 232)==
<StructureSection load='5pvh' size='340' side='right' caption='[[5pvh]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5pvh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5PVH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5pvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5pvh OCA], [http://pdbe.org/5pvh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5pvh RCSB], [http://www.ebi.ac.uk/pdbsum/5pvh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5pvh ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bradley, A R]]
[[Category: Brandao-Neto, J]]
[[Category: Brennan, P E]]
[[Category: Collins, P]]
[[Category: Cox, O]]
[[Category: Delft, F von]]
[[Category: Dias, A]]
[[Category: Douangamath, A]]
[[Category: Edwards, A]]
[[Category: Fairhead, M]]
[[Category: Krojer, T]]
[[Category: MacLean, E]]
[[Category: Ng, J]]
[[Category: Pearce, N M]]
[[Category: Renjie, Z]]
[[Category: Sethi, R]]
[[Category: Talon, R]]
[[Category: Wright, N]]
[[Category: Bromodomain]]
[[Category: Epigenetic]]
[[Category: Gene regulation]]
[[Category: Pandda]]
[[Category: Sgc - diamond i04-1 fragment screening]]
[[Category: Xchemexplorer]]