View source for 5j5d


==Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid==
<StructureSection load='5j5d' size='340' side='right' caption='[[5j5d]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5j5d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J5D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J5D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6GT:2-OXOHEPTANEDIOIC+ACID'>6GT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j5d OCA], [http://pdbe.org/5j5d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j5d RCSB], [http://www.ebi.ac.uk/pdbsum/5j5d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j5d ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DAPA_MYCTU DAPA_MYCTU]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (Probable).<ref>PMID:18062777</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
[[Category: Gopal, B]]
[[Category: Navratna, V]]
[[Category: Alpha-ketopimelic acid]]
[[Category: Dap pathway]]
[[Category: L-lysine]]
[[Category: Lyase]]