View source for 3sbf


==Crystal structure of the mutant P311A of enolase superfamily member from VIBRIONALES BACTERIUM complexed with Mg and D-Arabinonate==
<StructureSection load='3sbf' size='340' side='right' caption='[[3sbf]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sbf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrionales_bacterium_swat-3 Vibrionales bacterium swat-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8T:D-ARABINONIC+ACID'>D8T</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r25|3r25]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VSWAT3_13707 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391574 Vibrionales bacterium SWAT-3])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbf OCA], [http://pdbe.org/3sbf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sbf RCSB], [http://www.ebi.ac.uk/pdbsum/3sbf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbf ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/IMAND_VIBBS IMAND_VIBBS]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>  

==See Also==
*[[Mandelate racemase|Mandelate racemase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Vibrionales bacterium swat-3]]
[[Category: Almo, S C]]
[[Category: Fedorov, A A]]
[[Category: Fedorov, E V]]
[[Category: Gerlt, J A]]
[[Category: Wichelecki, D]]
[[Category: Acid sugar dehydratase]]
[[Category: D-araninonate]]
[[Category: Enolase fold]]
[[Category: Isomerase]]