View source for 4e3y


==X-ray structure of the Serratia marcescens endonuclease at 0.95 A resolution==
<StructureSection load='4e3y' size='340' side='right' caption='[[4e3y]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4e3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E3Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serratia_marcescens_nuclease Serratia marcescens nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.30.2 3.1.30.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e3y OCA], [http://pdbe.org/4e3y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e3y RCSB], [http://www.ebi.ac.uk/pdbsum/4e3y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e3y ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUCA_SERMA NUCA_SERMA]] Catalyzes the hydrolysis of both DNA and RNA, double- or single-stranded, at the 3'position of the phosphodiester bond to produce 5'-phosphorylated mono-, di-, tri- and tetranucleotides. DNA is a slightly better substrate than RNA. 
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</StructureSection>
[[Category: Serratia marcescens]]
[[Category: Serratia marcescens nuclease]]
[[Category: Balaev, V V]]
[[Category: Betzel, C]]
[[Category: Gabdoulkhakov, A G]]
[[Category: Lashkov, A A]]
[[Category: Mikhailov, A M]]
[[Category: Extracellular]]
[[Category: Hydrolase]]
[[Category: Nucleic acid]]
[[Category: Rossmann fold]]