View source for 3ma6


==Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1==
<StructureSection load='3ma6' size='340' side='right' caption='[[3ma6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ma6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MA6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDPK1, TGME49_101440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ma6 OCA], [http://pdbe.org/3ma6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ma6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ma6 ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3ma6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ma6 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Toxgo]]
[[Category: Amani, M]]
[[Category: Arrowsmith, C H]]
[[Category: Artz, J D]]
[[Category: Bochkarev, A]]
[[Category: Bountra, C]]
[[Category: Edwards, A M]]
[[Category: Hassani, A A]]
[[Category: Hui, R]]
[[Category: Lin, Y H]]
[[Category: Lourido, S]]
[[Category: Qiu, W]]
[[Category: Structural genomic]]
[[Category: Senisterra, G]]
[[Category: Shokat, K]]
[[Category: Sibley, L D]]
[[Category: Vedadi, M]]
[[Category: Weigelt, J]]
[[Category: Wernimont, A K]]
[[Category: Zhang, C]]
[[Category: Atp-binding]]
[[Category: Cdpk]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Parasitology]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Sgc]]
[[Category: Transferase]]