View source for 2bw9

[[Image:2bw9.gif|left|200px]]<br />
<applet load="2bw9" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="2bw9, resolution 1.68&Aring;" />
'''LAUE STRUCTURE OF L29W MBCO'''<br />

==Overview==
By using time-resolved x-ray crystallography at room temperature, structural relaxations and ligand migration were examined in myoglobin, (Mb) mutant L29W from nanoseconds to seconds after photodissociation of, carbon monoxide (CO) from the heme iron by nanosecond laser pulses. The, data were analyzed in terms of transient kinetics by fitting trial, functions to integrated difference electron density values obtained from, select structural moieties, thus allowing a quantitative description of, the processes involved. The observed relaxations are linked to other, investigations on protein dynamics. At the earliest times, the heme has, already completely relaxed into its domed deoxy structure, and there is no, photo-dissociated CO visible at the primary docking site. Initial, relaxations of ... [[http://ispc.weizmann.ac.il/pmbin/getpm?16085709 (full description)]]

==About this Structure==
2BW9 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Physeter_catodon Physeter catodon]] with HEM and CMO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BW9 OCA]]. 

==Reference==
Ligand migration pathway and protein dynamics in myoglobin: a time-resolved crystallographic study on L29W MbCO., Schmidt M, Nienhaus K, Pahl R, Krasselt A, Anderson S, Parak F, Nienhaus GU, Srajer V, Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11704-9. Epub 2005 Aug 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16085709 16085709]
[[Category: Physeter catodon]]
[[Category: Single protein]]
[[Category: Anderson, S.]]
[[Category: Krasselt, A.]]
[[Category: Nienhaus, G.U.]]
[[Category: Nienhaus, K.]]
[[Category: Pahl, R.]]
[[Category: Parak, F.]]
[[Category: Schmidt, M.]]
[[Category: Srajer, V.]]
[[Category: CMO]]
[[Category: HEM]]
[[Category: l29w mbco]]
[[Category: laue crystallography]]
[[Category: myoglobin mutant l29w]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:17:33 2007''