View source for 2otp

==Crystal Structure of Immunoglobulin-Like Transcript 1 (ILT1/LIR7/LILRA2)==
<StructureSection load='2otp' size='340' side='right' caption='[[2otp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2otp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OTP FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LILRA2, ILT1, LIR7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2otp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otp OCA], [http://pdbe.org/2otp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2otp RCSB], [http://www.ebi.ac.uk/pdbsum/2otp PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LIRA2_HUMAN LIRA2_HUMAN]] Does not bind class I MHC antigens.<ref>PMID:19230061</ref>  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/2otp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2otp ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Chen, Y]]
[[Category: Gao, F]]
[[Category: Gao, G F]]
[[Category: Liu, Y]]
[[Category: Peng, H]]
[[Category: Activating receptor]]
[[Category: Dimer]]
[[Category: Domain swapping]]
[[Category: Ilt1]]
[[Category: Immune system]]
[[Category: Monomer]]