View source for 2oo3

==Crystal structure of protein LPL1258 from Legionella pneumophila str. Philadelphia 1, Pfam DUF519==
<StructureSection load='2oo3' size='340' side='right' caption='[[2oo3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2oo3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila Legionella pneumophila subsp. pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OO3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpl1258, lpg1296, DSM 7513 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=91891 Legionella pneumophila subsp. pneumophila])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oo3 OCA], [http://pdbe.org/2oo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oo3 RCSB], [http://www.ebi.ac.uk/pdbsum/2oo3 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2oo3 TOPSAN]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/Q5ZVZ2_LEGPH Q5ZVZ2_LEGPH]] Specifically methylates the adenine in position 2030 of 23S rRNA.[HAMAP-Rule:MF_00934] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oo/2oo3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Legionella pneumophila subsp. pneumophila]]
[[Category: Almo, S C]]
[[Category: Atwell, S]]
[[Category: Bain, K T]]
[[Category: Bonanno, J B]]
[[Category: Burley, S K]]
[[Category: Freeman, J]]
[[Category: Structural genomic]]
[[Category: Ozyurt, S]]
[[Category: Reyes, C]]
[[Category: Sauder, J M]]
[[Category: Slocombe, A]]
[[Category: Smyth, L]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]