View source for 2pfh

[[Image:2pfh.gif|left|200px]]

 {{Structure
|PDB= 2pfh |SIZE=350|CAPTION= <scene name='initialview01'>2pfh</scene>, resolution 0.85&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene>, <scene name='pdbligand=FID:(2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE'>FID</scene> and <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] 
|GENE= AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}

'''Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.'''


==About this Structure==
2PFH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFH OCA]. 
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Cousido, A.]]
[[Category: Ginell, S.]]
[[Category: Hazemann, I.]]
[[Category: Joachimiak, A.]]
[[Category: Mitschler, A.]]
[[Category: Petrova, T.]]
[[Category: Podjarny, A.]]
[[Category: CIT]]
[[Category: CL]]
[[Category: FID]]
[[Category: LDT]]
[[Category: NDP]]
[[Category: fidarestat]]
[[Category: idd594]]
[[Category: nadp]]
[[Category: oxidoreductase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:12:19 2008''