View source for 2ieh

[[Image:2ieh.gif|left|200px]]

 {{Structure
|PDB= 2ieh |SIZE=350|CAPTION= <scene name='initialview01'>2ieh</scene>, resolution 2.7&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MOY:[(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE'>MOY</scene> and <scene name='pdbligand=PG4:TETRAETHYLENE GLYCOL'>PG4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Plus-end-directed_kinesin_ATPase Plus-end-directed kinesin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.4 3.6.4.4] 
|GENE= KIF11, EG5, KNSL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}

'''Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer'''


==About this Structure==
2IEH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEH OCA]. 
[[Category: Homo sapiens]]
[[Category: Plus-end-directed kinesin ATPase]]
[[Category: Single protein]]
[[Category: Garcia-Saez, I.]]
[[Category: Kozielski, F.]]
[[Category: ADP]]
[[Category: CL]]
[[Category: K]]
[[Category: MG]]
[[Category: MOY]]
[[Category: PG4]]
[[Category: beta-sheet core]]
[[Category: flanked by three alpha-helices on each side]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:28:33 2008''