View source for 4rv4

==2.65 Angstrom Resolution Crystal Structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor' in complex with 5-phospho-alpha-D-ribosyl diphosphate (PRPP)==
<StructureSection load='4rv4' size='340' side='right' caption='[[4rv4]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4rv4]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3osc 3osc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RV4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m3h|3m3h]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rv4 RCSB], [http://www.ebi.ac.uk/pdbsum/4rv4 PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PYRE_BACAN PYRE_BACAN]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity). 
__TOC__
</StructureSection>
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Anderson, W F]]
[[Category: Structural genomic]]
[[Category: Halavaty, A S]]
[[Category: Minasov, G]]
[[Category: Shuvalova, L]]
[[Category: Winsor, J]]
[[Category: Csgid]]
[[Category: Glycosyltransferase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Transferase]]