View source for 2cue

[[Image:2cue.gif|left|200px]]

 {{Structure
|PDB= 2cue |SIZE=350|CAPTION= <scene name='initialview01'>2cue</scene>
|SITE= 
|LIGAND= 
|ACTIVITY= 
|GENE= PAX6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}

'''Solution structure of the homeobox domain of the human paired box protein Pax-6'''


==Disease==
Known diseases associated with this structure: Aniridia, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Cataract, congenital, with late-onset corneal dystrophy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Coloboma, ocular OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Ectopia pupillae OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Eye anomalies, multiplex OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Foveal hypoplasia, isolated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Keratitis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Morning glory disc anomaly OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Optic nerve hypoplasia/aplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]], Peters anomaly OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607108 607108]]

==About this Structure==
2CUE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUE OCA]. 
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Inoue, M.]]
[[Category: Kigawa, T.]]
[[Category: Koshiba, S.]]
[[Category: Ohnishi, S.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tochio, N.]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama, S.]]
[[Category: homeobox domain]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: paired box protein]]
[[Category: pax6]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription factor]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:19:55 2008''