View source for 4hcb

==The metal-free form of crystal structure of E.coli ExoI-ssDNA complex==
<StructureSection load='4hcb' size='340' side='right' caption='[[4hcb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hcb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HCB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hcc|4hcc]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2011, cpeA, JW1993, sbcB, xonA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=668369 Escherichia coli DH5[alpha]])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_I Exodeoxyribonuclease I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.1 3.1.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hcb RCSB], [http://www.ebi.ac.uk/pdbsum/4hcb PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/EX1_ECOLI EX1_ECOLI]] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase. 
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</StructureSection>
[[Category: Exodeoxyribonuclease I]]
[[Category: Gong, W]]
[[Category: Ji, C]]
[[Category: Liu, M]]
[[Category: Lou, T]]
[[Category: Qiu, R]]
[[Category: Wei, J]]
[[Category: 3'-5' exonuclease]]
[[Category: Dnaq family]]
[[Category: Exonuclease c-terminal family]]
[[Category: Hydrolase-dna complex]]