View source for 3sms

==Human Pantothenate kinase 3 in complex with a pantothenate analog==
<StructureSection load='3sms' size='340' side='right' caption='[[3sms]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SMS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RNH:(2R)-N-[3-(HEPTYLAMINO)-3-OXOPROPYL]-2,4-DIHYDROXY-3,3-DIMETHYLBUTANAMIDE'>RNH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sms RCSB], [http://www.ebi.ac.uk/pdbsum/3sms PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PANK3_HUMAN PANK3_HUMAN]] Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity). 

==See Also==
*[[Pantothenate kinase|Pantothenate kinase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Pantothenate kinase]]
[[Category: Arrowsmith, C H]]
[[Category: Bolshan, Y]]
[[Category: Bountra, C]]
[[Category: Edwards, A M]]
[[Category: Hong, B]]
[[Category: Mottaghi, K]]
[[Category: Park, H]]
[[Category: Structural genomic]]
[[Category: Smil, D]]
[[Category: Tempel, W]]
[[Category: Weigelt, J]]
[[Category: Wernimont, A K]]
[[Category: Sgc]]
[[Category: Transferase]]