View source for 1xo8

[[Image:1xo8.jpg|left|200px]]

 {{Structure
|PDB= 1xo8 |SIZE=350|CAPTION= <scene name='initialview01'>1xo8</scene>
|SITE= 
|LIGAND= 
|ACTIVITY= 
|GENE= 
}}

'''Solution structure of AT1g01470 from Arabidopsis Thaliana'''


==Overview==
We report the three-dimensional structure of a late embryogenesis abundant (LEA) protein from Arabidopsis thaliana gene At1g01470.1. This protein is a member of Pfam cluster PF03168, and has been classified as a LEA14 protein. LEA proteins are expressed under conditions of cellular stress, such as desiccation, cold, osmotic stress, and heat. The structure, which was determined by NMR spectroscopy, revealed that the At1g01470.1 protein has an alphabeta-fold consisting of one alpha-helix and seven beta-strands that form two antiparallel beta-sheets. The closest structural homologs were discovered to be fibronectin Type III domains, which have &lt;7% sequence identity. Because fibronectins from animal cells have been shown to be involved in cell adhesion, cell motility, wound healing, and maintenance of cell shape, it is interesting to note that in plants wounding or stress results in the overexpression of a protein with fibronectin Type III structural features.

==About this Structure==
1XO8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO8 OCA]. 

==Reference==
Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein., Singh S, Cornilescu CC, Tyler RC, Cornilescu G, Tonelli M, Lee MS, Markley JL, Protein Sci. 2005 Oct;14(10):2601-9. Epub 2005 Sep 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16155204 16155204]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Cornilescu, C C.]]
[[Category: Cornilescu, G.]]
[[Category: Lee, M S.]]
[[Category: Markley, J L.]]
[[Category: Singh, S.]]
[[Category: Tonelli, M.]]
[[Category: Tyler, R C.]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: unknown function]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:12:25 2008''