View source for 4fhq

==Crystal Structure of HVEM==
<StructureSection load='4fhq' size='340' side='right' caption='[[4fhq]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fhq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FHQ FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2aw2|2aw2]], [[1jma|1jma]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HVEA, HVEM, TNFRSF14, UNQ329/PRO509 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fhq RCSB], [http://www.ebi.ac.uk/pdbsum/4fhq PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TNR14_HUMAN TNR14_HUMAN]] Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.<ref>PMID:8898196</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Almo, S C]]
[[Category: Bhosle, R C]]
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network]]
[[Category: Liu, W]]
[[Category: Structural genomic]]
[[Category: Nathenson, S G]]
[[Category: Patskovsky, Y]]
[[Category: Zhan, C]]
[[Category: Atoms-to-animals: the immune function network]]
[[Category: Btla]]
[[Category: Cd160]]
[[Category: Cysteine rich domain]]
[[Category: Gd of hsv]]
[[Category: Ifn]]
[[Category: Immune system]]
[[Category: Membrane]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Receptor]]
[[Category: Tnf receptor]]
[[Category: Tnf14]]
[[Category: Tnfrsf]]