View source for 3vfb

==Crystal Structure of HIV-1 Protease Mutant N88D with novel P1'-Ligands GRL-02031==
<StructureSection load='3vfb' size='340' side='right' caption='[[3vfb]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vfb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(bru_isolate) Human immunodeficiency virus type 1 (bru isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VFB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=031:(3AS,5R,6AR)-HEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-([(4-METHOXYPHENYL)SULFONYL]{[(2R)-5-OXOPYRROLIDIN-2-YL]METHYL}AMINO)PROPYL]CARBAMATE'>031</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h5b|3h5b]], [[3vf5|3vf5]], [[3vf7|3vf7]], [[3vfa|3vfa]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 Human immunodeficiency virus type 1 (BRU ISOLATE)])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vfb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vfb RCSB], [http://www.ebi.ac.uk/pdbsum/3vfb PDBsum]</span></td></tr>
</table>

==See Also==
*[[Virus protease|Virus protease]]
__TOC__
</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: Chang, Y C.E]]
[[Category: Wang, Y F]]
[[Category: Weber, I T]]
[[Category: Yu, X X]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: P1'-ligand]]
[[Category: Protease inhibitor]]