View source for 1ljp

[[Image:1ljp.jpg|left|200px]]

 {{Structure
|PDB= 1ljp |SIZE=350|CAPTION= <scene name='initialview01'>1ljp</scene>, resolution 1.80&Aring;
|SITE= 
|LIGAND= 
|ACTIVITY= 
|GENE= cin1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4785 Phytophthora cinnamomi])
}}

'''Crystal Structure of beta-Cinnamomin Elicitin'''


==Overview==
Phytophthora and Pythium species are among the most aggressive plant pathogens, as they invade many economically important crops and forest trees. They secrete large amounts of 10 kDa proteins called elicitins that can act as elicitors of plant defence mechanisms. These proteins may also induce a hypersensitive response (HR) including plant cell necrosis, with different levels of toxicity depending on their pI. Recent studies showed that elicitins function as sterol carrier proteins. The crystallographic structure of the highly necrotic recombinant beta-cinnamomin (beta-CIN) from Phytophthora cinnamomi has been determined at 1.8 A resolution using the molecular-replacement method. beta-CIN has the same overall structure as beta-cryptogein (beta-CRY), an elicitin secreted by Phytophthora cryptogea, although it shows a different surface electrostatic potential distribution. The protein was expressed in Pichia pastoris and crystallized in the triclinic space group with two monomers in the asymmetric unit. The interface formed by these two monomers resembles that from beta-CRY dimer, although with fewer interactions.

==About this Structure==
1LJP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Phytophthora_cinnamomi Phytophthora cinnamomi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LJP OCA]. 

==Reference==
Structure of beta-cinnamomin, a protein toxic to some plant species., Rodrigues ML, Archer M, Martel P, Jacquet A, Cravador A, Carrondo MA, Acta Crystallogr D Biol Crystallogr. 2002 Aug;58(Pt 8):1314-21. Epub 2002, Jul 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12136143 12136143]
[[Category: Phytophthora cinnamomi]]
[[Category: Single protein]]
[[Category: Archer, M.]]
[[Category: Carrondo, M A.]]
[[Category: Cravador, A.]]
[[Category: Jacquet, A.]]
[[Category: Martel, P.]]
[[Category: Rodrigues, M L.]]
[[Category: elicitin]]
[[Category: phytopathogen]]
[[Category: sterol carrier protein]]

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