View source for 4r91

==BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((1S,3R)-3-(cyclopentylamino)cyclohexyl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium==
<StructureSection load='4r91' size='340' side='right' caption='[[4r91]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4r91]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R91 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3KT:(2E,5R)-5-(2-CYCLOHEXYLETHYL)-5-{[(1S,3R)-3-(CYCLOPENTYLAMINO)CYCLOHEXYL]METHYL}-2-IMINO-3-METHYLIMIDAZOLIDIN-4-ONE'>3KT</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r8y|4r8y]], [[4r92|4r92]], [[4r93|4r93]], [[4r95|4r95]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r91 RCSB], [http://www.ebi.ac.uk/pdbsum/4r91 PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Memapsin 2]]
[[Category: Caldwell, J P.]]
[[Category: Orth, P.]]
[[Category: Strickland, C.]]
[[Category: Aspartic protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]