View source for 2k79

==Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase==
<StructureSection load='2k79' size='340' side='right' caption='[[2k79]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2k79]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K79 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K79 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1luk|1luk]], [[1lun|1lun]], [[2rna|2rna]], [[1awj|1awj]], [[2etz|2etz]], [[2k7a|2k7a]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Itk, Emt, Tlk, Tsk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k79 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k79 RCSB], [http://www.ebi.ac.uk/pdbsum/2k79 PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k79_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Tyrosine kinase|Tyrosine kinase]]
__TOC__
</StructureSection>
[[Category: Mus musculus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Andreotti, A H.]]
[[Category: Fulton, D B.]]
[[Category: Severin, A J.]]
[[Category: Atp-binding]]
[[Category: Cell membrane]]
[[Category: Cis]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Novel]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Sh2]]
[[Category: Sh2 domain]]
[[Category: Sh3]]
[[Category: Sh3 domain]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Zinc-finger]]