View source for 2jd7

[[Image:2jd7.gif|left|200px]]<br />
<applet load="2jd7" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="2jd7, resolution 2.80&Aring;" />
'''CRYSTAL STRUCTURE OF THE FE-SOAKED FERRITIN FROM THE HYPERTHERMOPHILIC ARCHAEAL ANAEROBE PYROCOCCUS FURIOSUS'''<br />

==Overview==
The crystal structure of the ferritin from the archaeon, hyperthermophile, and anaerobe Pyrococcus furiosus (PfFtn) is presented. While many ferritin, structures from bacteria to mammals have been reported, until now only one, was available from archaea, the ferritin from Archaeoglobus fulgidus, (AfFtn). The PfFtn 24-mer exhibits the 432 point-group symmetry that is, characteristic of most ferritins, which suggests that the 23 symmetry, found in the previously reported AfFtn is not a common feature of archaeal, ferritins. Consequently, the four large pores that were found in AfFtn are, not present in PfFtn. The structure has been solved by molecular, replacement and refined at 2.75-A resolution to R = 0.195 and R (free) =, 0.247. The ferroxidase center of the aerobically crystallized ... [[http://ispc.weizmann.ac.il/pmbin/getpm?17541801 (full description)]]

==About this Structure==
2JD7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]] with FE and SO4 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JD7 OCA]]. 

==Reference==
Crystal structure of the ferritin from the hyperthermophilic archaeal anaerobe Pyrococcus furiosus., Tatur J, Hagen WR, Matias PM, J Biol Inorg Chem. 2007 Jun;12(5):615-30. Epub 2007 Feb 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17541801 17541801]
[[Category: Pyrococcus furiosus]]
[[Category: Single protein]]
[[Category: Hagen, W.R.]]
[[Category: Matias, P.M.]]
[[Category: Tatur, J.]]
[[Category: FE]]
[[Category: SO4]]
[[Category: archaeon]]
[[Category: entry channels]]
[[Category: ferritin]]
[[Category: ferroxidase center metal transport]]
[[Category: hyperthermophile]]
[[Category: iron]]
[[Category: pores]]
[[Category: thermostability]]

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