View source for 3c5k

==Crystal structure of human HDAC6 zinc finger domain==
<StructureSection load='3c5k' size='340' side='right' caption='[[3c5k]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3c5k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C5K FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDAC6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c5k RCSB], [http://www.ebi.ac.uk/pdbsum/3c5k PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Histone deacetylase|Histone deacetylase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Bochkarev, A.]]
[[Category: Bountra, C.]]
[[Category: Dhe-Paganon, S.]]
[[Category: Dong, A.]]
[[Category: Edwards, A M.]]
[[Category: Kozieradzki, I.]]
[[Category: Li, Y.]]
[[Category: Loppnau, P.]]
[[Category: MacKenzie, F.]]
[[Category: Min, J.]]
[[Category: Ouyang, H.]]
[[Category: Ravichandran, M.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Schuetz, A.]]
[[Category: Weigelt, J.]]
[[Category: Actin-binding]]
[[Category: Chromatin regulator]]
[[Category: Hdac6]]
[[Category: Hydrolase]]
[[Category: Metal-binding]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Repressor]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Zinc finger]]
[[Category: Zinc-finger]]