View source for 1fer

[[Image:1fer.jpg|left|200px]]

 {{Structure
|PDB= 1fer |SIZE=350|CAPTION= <scene name='initialview01'>1fer</scene>, resolution 2.3&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene> and <scene name='pdbligand=SF4:IRON/SULFUR CLUSTER'>SF4</scene>
|ACTIVITY= 
|GENE= 
}}

'''STRUCTURE AT PH 6.5 OF FERREDOXIN I FROM AZOTOBACTER VINELANDII AT 2.3 ANGSTROMS RESOLUTION'''


==Overview==
Ferredoxin I from Azotobacter vinelandii (AvFdI) is an iron-sulfur protein composed of 106 amino acids, seven Fe atoms and eight inorganic S* atoms. A crystallographic redetermination of its structure showed the originally reported structure to be incorrect. We report here the crystal structure of AvFdI at pH 6.5. Extensive refinement has led to a final R value of 0.170 for all 6986 non-extinct reflections in the range 10-2.3 A using a solvent model which includes 98 discrete solvent atoms with occupancies between 0.3 and 1.0 and an average B value of 22.5 A(2). The first half of the peptide chain closely resembles that of the 55-residue ferredoxin from Peptococcus aerogenes (PaFd), while the remainder consists of three turns of helix and a series of loops which form a cap over part of the molecular core. Despite the similarities in structure and surroundings, the corresponding 4Fe4S* clusters in PaFd and AvFdI have strikingly different redox potentials; a possible explanation has been sought in the differing hydration models for the two molecules.

==About this Structure==
1FER is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FER OCA]. 

==Reference==
Structure at pH 6.5 of ferredoxin I from Azotobacter vinelandii at 2.3 A resolution., Merritt EA, Stout GH, Turley S, Sieker LC, Jehsen LH, Orme-Johnson WH, Acta Crystallogr D Biol Crystallogr. 1993 Mar 1;49(Pt 2):272-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299532 15299532]
[[Category: Azotobacter vinelandii]]
[[Category: Single protein]]
[[Category: Jensen, L H.]]
[[Category: Merritt, E A.]]
[[Category: Orme-Johnson, W H.]]
[[Category: Sieker, L C.]]
[[Category: Stout, G H.]]
[[Category: Turley, S.]]
[[Category: F3S]]
[[Category: SF4]]
[[Category: electron transfer(iron-sulfur protein)]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:08:06 2008''