View source for 1ewy

[[Image:1ewy.jpg|left|200px]]

 {{Structure
|PDB= 1ewy |SIZE=350|CAPTION= <scene name='initialview01'>1ewy</scene>, resolution 2.38&Aring;
|SITE= 
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=FES:FE2/S2 (INORGANIC) CLUSTER'>FES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ferredoxin--NADP(+)_reductase Ferredoxin--NADP(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.2 1.18.1.2] 
|GENE= 
}}

'''ANABAENA PCC7119 FERREDOXIN:FERREDOXIN-NADP+-REDUCTASE COMPLEX'''


==Overview==
Ferredoxin-NADP(+) reductase (FNR) and its physiological electron donor ferredoxin (Fd) from the cyanobacterium Anabaena PCC7119 have been co-crystallized. The unit-cell parameters are a = b = 63.72, c = 158.02 A and the space group is P2(1)2(1)2(1). The crystal structure has been solved with 2.4 A resolution synchrotron data by molecular replacement, anomalous dispersion and R(min) search methods. For the computations, the crystal was treated as a merohedral twin. The asymmetric unit contains two FNR molecules and one ferredoxin molecule. The packing of the FNR molecules displays a nearly tetragonal symmetry (space group P4(3)2(1)2), whereas the ferredoxin arrangement is orthorhombic. This study provides the first crystallographic model of a dissociable complex between FNR and Fd.

==About this Structure==
1EWY is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Nostoc_sp._pcc_7119 Nostoc sp. pcc 7119]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EWY OCA]. 

==Reference==
Crystallographic studies of the interaction between the ferredoxin-NADP+ reductase and ferredoxin from the cyanobacterium Anabaena: looking for the elusive ferredoxin molecule., Morales R, Kachalova G, Vellieux F, Charon MH, Frey M, Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1408-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11053838 11053838]
[[Category: Ferredoxin--NADP(+) reductase]]
[[Category: Nostoc sp. pcc 7119]]
[[Category: Protein complex]]
[[Category: Charon, M H.]]
[[Category: Frey, M.]]
[[Category: Morales, R.]]
[[Category: FAD]]
[[Category: FES]]
[[Category: electron transfer complex]]
[[Category: ferredoxin]]
[[Category: photosynthesis]]
[[Category: protein-protein interaction]]
[[Category: reductase]]

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