View source for 1k0n

{{STRUCTURE_1k0n|  PDB=1k0n  |  SCENE=  }} 
===Chloride Intracellular Channel 1 (CLIC1) complexed with glutathione===
{{ABSTRACT_PUBMED_11551966}}

==Function==
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>  

==About this Structure==
[[1k0n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0N OCA]. 

==Reference==
<ref group="xtra">PMID:011551966</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Bauskin, A R.]]
[[Category: Breit, S N.]]
[[Category: Campbell, T J.]]
[[Category: Curmi, P M.G.]]
[[Category: DeMaere, M Z.]]
[[Category: Fairlie, W D.]]
[[Category: Harrop, S J.]]
[[Category: Jankova, L.]]
[[Category: Mazzanti, M.]]
[[Category: Pankhurst, S.]]
[[Category: Qiu, M R.]]
[[Category: Reztsova, T.]]
[[Category: Tonini, R.]]
[[Category: Valenzuela, S M.]]
[[Category: Warton, K.]]
[[Category: Wu, W M.]]
[[Category: Chloride ion channel]]
[[Category: Clic1]]
[[Category: Glutathione]]
[[Category: Glutathione-s-tranferase superfamily]]
[[Category: Metal transport]]
[[Category: Ncc27]]