View source for 4omc

{{STRUCTURE_4omc|  PDB=4omc  |  SCENE=  }} 
===X-ray structure of human furin in complex with the competitive inhibitor meta-guanidinomethyl-Phac-RVR-Amba===
{{ABSTRACT_PUBMED_24666235}}

==Function==
[[http://www.uniprot.org/uniprot/FURIN_HUMAN FURIN_HUMAN]] Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.<ref>PMID:7690548</ref>  

==About this Structure==
[[4omc]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OMC OCA]. 

==Reference==
<ref group="xtra">PMID:024666235</ref><references group="xtra"/><references/>
[[Category: Furin]]
[[Category: Dahms, S O.]]
[[Category: Than, M E.]]
[[Category: Competitive inhibitor]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Pro-protein convertase]]
[[Category: Protease-inhibitor complex]]
[[Category: Serine protease]]