View source for 4myq

{{STRUCTURE_4myq|  PDB=4myq  |  SCENE=  }} 
===Selective Inhibition of the Catalytic Domain Of Human Phosphodiesterase 4B With A-33===

==Function==
[[http://www.uniprot.org/uniprot/PDE4B_HUMAN PDE4B_HUMAN]] Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.<ref>PMID:10846163</ref> <ref>PMID:15003452</ref>  

==About this Structure==
[[4myq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MYQ OCA]. 

==Reference==
<references group="xtra"/><references/>
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Edwards, T E.]]
[[Category: III, D Fox.]]
[[Category: Catalytic]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Phosphodiesterase]]