View source for 4kh5

{{STRUCTURE_4kh5|  PDB=4kh5  |  SCENE=  }} 
===Toxoplasma gondii NTPDase1 C258S/C268S in complex with Mg and AMPNP===
{{ABSTRACT_PUBMED_24115522}}

==Function==
[[http://www.uniprot.org/uniprot/NTP2_TOXGO NTP2_TOXGO]] May perform an important processing step in the conversion of high energy nucleotides prior to uptake by the parasite. NTPAse-II has a specific activity 4.5-fold lower than NTPAse-I in hydrolysis of ATP. The primary difference between these isozymes lies in their ability to hydrolyze nucleoside triphosphate versus diphosphate substrates. While NTPAse-II hydrolyzes ATP to ADP and ADP to AMP at almost the same rate, NTPAse-I hydrolyzes ADP to AMP at a much slower rate (0.7% of the rate for ATP). 

==About this Structure==
[[4kh5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KH5 OCA]. 

==Reference==
<ref group="xtra">PMID:024115522</ref><references group="xtra"/><references/>
[[Category: Nucleoside-triphosphatase]]
[[Category: Toxgo]]
[[Category: Krug, U.]]
[[Category: Strater, N.]]
[[Category: Totzauer, R.]]
[[Category: Actin-like fold]]
[[Category: Hydrolase]]
[[Category: Ntpdase]]