View source for 2p6x

[[Image:2p6x.jpg|left|200px]]<br /><applet load="2p6x" size="350" color="white" frame="true" align="right" spinBox="true" 
caption="2p6x, resolution 1.90&Aring;" />
'''Crystal structure of human tyrosine phosphatase PTPN22'''<br />

==Disease==
Known diseases associated with this structure: Diabetes mellitus, insulin-dependent, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Systemic lupus erythematosus, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]]

==About this Structure==
2P6X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P6X OCA]. 
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Single protein]]
[[Category: Alfano, I.]]
[[Category: Arrowsmith, C H.]]
[[Category: Barr, A.]]
[[Category: Bunkoczi, G.]]
[[Category: Burgess-Brown, N.]]
[[Category: Delft, F von.]]
[[Category: Edwards, A.]]
[[Category: King, O.]]
[[Category: Knapp, S.]]
[[Category: Papagrigoriou, E.]]
[[Category: Pike, A C.W.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Salah, E.]]
[[Category: Shrestha, L.]]
[[Category: Sundstrom, M.]]
[[Category: Turnbull, A.]]
[[Category: Ugochukwu, E.]]
[[Category: Umeano, C.]]
[[Category: Uppenberg, J.]]
[[Category: Weigelt, J.]]
[[Category: CL]]
[[Category: EDO]]
[[Category: lymphoid phosphatase]]
[[Category: lyp]]
[[Category: pep]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
[[Category: tyrosine phosphatase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:26:30 2008''