View source for 4jsl

{{STRUCTURE_4jsl|  PDB=4jsl  |  SCENE=  }} 
===Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6,6'-(heptane-1,7-diyl)bis(4-methylpyridin-2-amine)===
{{ABSTRACT_PUBMED_23867386}}

==Function==
[[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. 

==About this Structure==
[[4jsl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JSL OCA]. 

==Reference==
<ref group="xtra">PMID:023867386</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Li, H.]]
[[Category: Poulos, T L.]]
[[Category: Nitric oxide synthase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]