View source for Stromal Derived Factor 1

[[Image:2kec.jpg|left|thumb|300px|NMR Structure of the Stromal cell-derived factor 1α, [[2kec]]]]
{{STRUCTURE_1qg7|right| PDB=1qg7  |  SCENE= |CAPTION=Stromal cell-derived factor 1α dimer complex with sulfate, [[1qg7]] }}



























[[Stromal Derived Factor 1]] (SDF-1α) or CXCL12 is a small cytokine from the chemokine family. It is natural ligand of [[CXC chemokine receptor type 4|CXCR4]] It has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis. The images on the left and right  correspond to one representative SDF-1α structure, ''i.e.'' the human SDF-1α ([[2kec]]).

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== 3D Structures of Stromal Derived Factor 1 ==

Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

[[2kec]], [[2ked]], [[2kee]], [[2sdf]], [[1sdf]], [[1vmc]] - hSDF1α – NMR - human<br />
[[1qg7]], [[3hp3]] - hSDF1α<br />
[[2k0l]], [[2k01]], [[2kol]] – hSDF1α (mutant) – NMR<br />
[[1a15]], [[3gv3]] - hSDF1α (mutant)<br />
[[2nwg]] - hSDF1α+heparin<br />
[[2j7z]] - hSDF1α residues 22-89<br />
[[2k03]], [[2k04]], [[2k05]] - hSDF1α (mutant)+ hCXCR4 N-terminal (mutant)<br />

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