View source for 3lzc

{{STRUCTURE_3lzc|  PDB=3lzc  |  SCENE=  }} 
===Crystal structure of Dph2 from Pyrococcus horikoshii===
{{ABSTRACT_PUBMED_20559380}}

==Function==
[[http://www.uniprot.org/uniprot/O58832_PYRHO O58832_PYRHO]] Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).<ref>PMID:20559380</ref>  

==About this Structure==
[[3lzc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA]. 

==Reference==
<ref group="xtra">PMID:020559380</ref><references group="xtra"/><references/>
[[Category: Pyrococcus horikoshii]]
[[Category: Dzikovski, B.]]
[[Category: Ealick, S E.]]
[[Category: Freed, J.]]
[[Category: Koralewski, R M.]]
[[Category: Krebs, C.]]
[[Category: Lee, M.]]
[[Category: Lin, H.]]
[[Category: Torelli, A T.]]
[[Category: Wang, E.]]
[[Category: Zhang, Y.]]
[[Category: Zhu, X.]]
[[Category: Biosynthetic protein]]
[[Category: Diphthamide biosynthesis]]
[[Category: Gene triplication]]
[[Category: Radical sam enzyme]]