View source for 2cov

[[Image:2cov.gif|left|200px]]<br /><applet load="2cov" size="350" color="white" frame="true" align="right" spinBox="true" 
caption="2cov, resolution 1.25&Aring;" />
'''Crystal structure of CBM31 from beta-1,3-xylanase'''<br />

==Overview==
Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds.

==About this Structure==
2COV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA]. 

==Reference==
The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan., Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M, FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16061225 16061225]
[[Category: Alcaligenes sp.]]
[[Category: Single protein]]
[[Category: Araki, T.]]
[[Category: Hashimoto, H.]]
[[Category: Okazaki, F.]]
[[Category: Sato, M.]]
[[Category: Shimizu, T.]]
[[Category: Tamai, Y.]]
[[Category: Tamaru, Y.]]
[[Category: 3-xylanase]]
[[Category: beta-1]]
[[Category: carbohydrate-binding module]]
[[Category: family 31 cbm]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:50:56 2008''