View source for 1f05

{{STRUCTURE_1f05|  PDB=1f05  |  SCENE=  }} 
===CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE===
{{ABSTRACT_PUBMED_10869557}}

==Disease==
[[http://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN]] Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:[http://omim.org/entry/606003 606003]]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. 

==Function==
[[http://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN]] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. 

==About this Structure==
[[1f05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F05 OCA]. 

==Reference==
<ref group="xtra">PMID:010869557</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Transaldolase]]
[[Category: Schneider, G.]]
[[Category: Thorell, S.]]
[[Category: Alpha-beta barrel]]
[[Category: Transferase]]