View source for 1rec

[[Image:1rec.gif|left|200px]]<br /><applet load="1rec" size="350" color="white" frame="true" align="right" spinBox="true" 
caption="1rec, resolution 1.9&Aring;" />
'''THREE-DIMENSIONAL STRUCTURE OF RECOVERIN, A CALCIUM SENSOR IN VISION'''<br />

==Overview==
Recoverin, a recently discovered member of the EF hand superfamily, serves as a calcium sensor in vision. We report here the crystal structure of recombinant unmyristoylated recoverin at 1.9 A resolution. The four EF hands of the protein are arranged in a compact array that contrasts with the dumbbell shape of calmodulin and troponin C. A calcium ion is bound to EF hand 3, while EF hand 2 can bind samarium but not calcium in this crystal form. The other two EF hands have novel structural features that prevent or impair calcium binding. A concave hydrophobic surface formed by EF hands 1 and 2 may participate in the read out of calcium signals by recoverin and its homologs.

==About this Structure==
1REC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1REC OCA]. 

==Reference==
Three-dimensional structure of recoverin, a calcium sensor in vision., Flaherty KM, Zozulya S, Stryer L, McKay DB, Cell. 1993 Nov 19;75(4):709-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8242744 8242744]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Flaherty, K M.]]
[[Category: Mckay, D B.]]
[[Category: Stryer, L.]]
[[Category: Zozulya, S.]]
[[Category: CA]]
[[Category: calcium-binding protein]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:49:56 2008''