View source for 1gyd

[[Image:1gyd.jpg|left|200px]]<br /><applet load="1gyd" size="350" color="white" frame="true" align="right" spinBox="true" 
caption="1gyd, resolution 2.05&Aring;" />
'''STRUCTURE OF CELLVIBRIO CELLULOSA ALPHA-L-ARABINANASE'''<br />

==Overview==
Cellvibrio japonicus arabinanase Arb43A hydrolyzes the alpha-1,5-linked L-arabinofuranoside backbone of plant cell wall arabinans. The three-dimensional structure of Arb43A, determined at 1.9 A resolution, reveals a five-bladed beta-propeller fold. Arb43A is the first enzyme known to display this topology. A long V-shaped surface groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. Three carboxylates deep in the active site groove provide the general acid and base components for glycosidic bond hydrolysis with inversion of anomeric configuration.

==About this Structure==
1GYD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Active as [http://en.wikipedia.org/wiki/Arabinan_endo-1,5-alpha-L-arabinosidase Arabinan endo-1,5-alpha-L-arabinosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.99 3.2.1.99] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GYD OCA]. 

==Reference==
Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold., Nurizzo D, Turkenburg JP, Charnock SJ, Roberts SM, Dodson EJ, McKie VA, Taylor EJ, Gilbert HJ, Davies GJ, Nat Struct Biol. 2002 Sep;9(9):665-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12198486 12198486]
[[Category: Arabinan endo-1,5-alpha-L-arabinosidase]]
[[Category: Cellvibrio japonicus]]
[[Category: Single protein]]
[[Category: Charnock, S J.]]
[[Category: Davies, G J.]]
[[Category: Dodson, E J.]]
[[Category: Gilbert, H J.]]
[[Category: Mckie, V A.]]
[[Category: Nurizzo, D.]]
[[Category: Roberts, S M.]]
[[Category: Taylor, E J.]]
[[Category: Turkenburg, J P.]]
[[Category: arabinanase]]
[[Category: catalysis]]
[[Category: cellvibrio]]
[[Category: hydrolase]]
[[Category: propeller]]
[[Category: pseudomonas]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:55:29 2008''