View source for 2cib

[[Image:2cib.gif|left|200px]]<br />
<applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="2cib, resolution 1.50&Aring;" />
'''HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS'''<br />

==About this Structure==
2CIB is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]] with HEM and CM6 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA]]. 
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Sterol 14-demethylase]]
[[Category: Kim, Y.]]
[[Category: Kries, J.P.Von.]]
[[Category: Podust, L.M.]]
[[Category: Waterman, M.R.]]
[[Category: Yermalitskaya, L.V.]]
[[Category: CM6]]
[[Category: HEM]]
[[Category: heme]]
[[Category: heme lipid synthesis]]
[[Category: metal-binding]]
[[Category: monooxygenase]]
[[Category: nadp]]
[[Category: oxidoreductase]]
[[Category: protein-inhibitor complex]]
[[Category: steroid biosynthesis]]
[[Category: sterol biosynthesis]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:10:48 2007''