View source for 1gj4

[[Image:1gj4.png|left|200px]]

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{{STRUCTURE_1gj4|  PDB=1gj4  |  SCENE=  }} 

===SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN===


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{{ABSTRACT_PUBMED_11731301}}

==About this Structure==
[[1gj4]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GJ4 OCA]. 

==See Also==
*[[Hirudin]]

==Reference==
<ref group="xtra">PMID:11731301</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Allen, D.]]
[[Category: Breitenbucher, J G.]]
[[Category: Hui, H.]]
[[Category: Katz, B A.]]
[[Category: Luong, C.]]
[[Category: Mackman, R L.]]
[[Category: Martelli, A.]]
[[Category: McGee, D.]]
[[Category: Spencer, J R.]]
[[Category: Sprengeler, P A.]]
[[Category: Verner, E.]]
[[Category: Blood clotting]]
[[Category: Hydrolase]]
[[Category: Oxyanion hole water]]
[[Category: Shift of pka of his57]]
[[Category: Specificity]]
[[Category: Structure-based drug design]]
[[Category: Three-centered]]
[[Category: Thrombin]]
[[Category: Trypsin]]
[[Category: Urokinase]]
[[Category: Very short hydrogen bond]]
[[Category: Zn+2-mediated inhibition]]