View source for 8z85


==Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 1==
<StructureSection load='8z85' size='340' side='right'caption='[[8z85]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8z85]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thogoto_virus_(isolate_SiAr_126) Thogoto virus (isolate SiAr 126)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z85 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z85 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z85 OCA], [https://pdbe.org/8z85 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z85 RCSB], [https://www.ebi.ac.uk/pdbsum/8z85 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z85 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA_THOGV PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Chang T]]
[[Category: Chen X]]
[[Category: Xiong X]]
[[Category: Xue L]]