View source for 8xop


==Cryo-EM structure of ClpP1P2 in complex with ADEP1 from Streptomyces hawaiiensis==
<StructureSection load='8xop' size='340' side='right'caption='[[8xop]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xop]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hawaiiensis Streptomyces hawaiiensis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XOP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=MP8:(4R)-4-METHYL-L-PROLINE'>MP8</scene>, <scene name='pdbligand=OTT:(2E,4E,6E)-OCTA-2,4,6-TRIENOIC+ACID'>OTT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xop OCA], [https://pdbe.org/8xop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xop RCSB], [https://www.ebi.ac.uk/pdbsum/8xop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xop ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A5B9BGY8_9ACTN A0A5B9BGY8_9ACTN] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.[HAMAP-Rule:MF_00444]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces hawaiiensis]]
[[Category: Synthetic construct]]
[[Category: Long F]]
[[Category: Xu X]]