View source for 6wnt


==50S ribosomal subunit without free 5S rRNA and perturbed PTC==
<StructureSection load='6wnt' size='340' side='right'caption='[[6wnt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6wnt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WNT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wnt OCA], [https://pdbe.org/6wnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wnt RCSB], [https://www.ebi.ac.uk/pdbsum/6wnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wnt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL2_ECOLI RL2_ECOLI] One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.[HAMAP-Rule:MF_01320_B]  In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G.[HAMAP-Rule:MF_01320_B]

==See Also==
*[[Ribosome 3D structures|Ribosome 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Aleksashin NA]]
[[Category: Huang S]]
[[Category: Jaeger L]]
[[Category: Kefi A]]
[[Category: Klepacki D]]
[[Category: Korostelev AA]]
[[Category: Loveland AB]]
[[Category: Mankin AS]]
[[Category: Reier K]]
[[Category: Remme J]]
[[Category: Szal A]]
[[Category: Vazquez-Laslop N]]