View source for 6oru


==Crystal structure of Bira from S. aureus in complex with a acylsulfamide analogue of biotinyl-5'-AMP==
<StructureSection load='6oru' size='340' side='right'caption='[[6oru]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6oru]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ORU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ORU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.392&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N3G:N-{[4-(6-amino-9H-purin-9-yl)butyl]sulfamoyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide'>N3G</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6oru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oru OCA], [https://pdbe.org/6oru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6oru RCSB], [https://www.ebi.ac.uk/pdbsum/6oru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6oru ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A3A5LBF0_STAAU A0A3A5LBF0_STAAU] Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.[HAMAP-Rule:MF_00978]

==See Also==
*[[Biotin Protein Ligase 3D structures|Biotin Protein Ligase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Cini D]]
[[Category: Wilce MCJ]]