View source for 6bdf


==2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy==
<SX load='6bdf' size='340' side='right' viewer='molstar' caption='[[6bdf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6bdf]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BDF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bdf OCA], [https://pdbe.org/6bdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bdf RCSB], [https://www.ebi.ac.uk/pdbsum/6bdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bdf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSB_THEAC PSB_THEAC] Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The T.acidophilum proteasome is able to cleave oligopeptides after Tyr, Leu, Phe, and to a lesser extent after Glu and Arg. Thus, displays chymotrypsin-like activity and low level of caspase-like and trypsin-like activities.<ref>PMID:8999862</ref> 

==See Also==
*[[Proteasome 3D structures|Proteasome 3D structures]]
== References ==
<references/>
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</SX>
[[Category: Large Structures]]
[[Category: Thermoplasma acidophilum]]
[[Category: Campbell MG]]
[[Category: Carragher B]]
[[Category: Cheng A]]
[[Category: Potter CS]]
[[Category: Veesler D]]