View source for 5ys6


==Structure of the ectodomain of pseudorabies virus glycoproten B==
<StructureSection load='5ys6' size='340' side='right'caption='[[5ys6]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ys6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Suid_alphaherpesvirus_1 Suid alphaherpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YS6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ys6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ys6 OCA], [https://pdbe.org/5ys6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ys6 RCSB], [https://www.ebi.ac.uk/pdbsum/5ys6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ys6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/T2FL65_9ALPH T2FL65_9ALPH] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.[HAMAP-Rule:MF_04032]

==See Also==
*[[Glycoproteins B and D|Glycoproteins B and D]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Suid alphaherpesvirus 1]]
[[Category: Hu XL]]
[[Category: Yang FL]]